The Cubs drafted Prior second overall in 2001 and he soon became one of the National League's best pitchers. He posted a 2.43 ERA with 10.4 K/9 and 2.1 BB/9 as a 22-year-old just a year and a half after being drafted. A series of shoulder problems derailed Prior's career, but he has tried to resurrect it with stints in the Padres', Rangers' and Yankees' systems. Now 31, he's attempting another comeback.
Ben Nicholson-Smith contributed to this post.