This will be the third White Sox tour for Santiago, whom the team selected in the 30th round of the 2006 draft. Santiago wound up pitching with the White Sox from 2011-13, during which he notched a 3.41 ERA/4.49 FIP in 224 2/3 innings.
Chicago dealt Santiago to the Angels in a noteworthy three-team trade heading into the 2014 campaign. After stints with the Halos and Twins, Santiago returned to the Sox on a minors deal in February 2018. He went on to throw 102 innings (49 appearances, seven starts) of 4.41 ERA/5.09 FIP ball with 9.09 K/9 and 5.29 BB/9 at the big league level last season.
Now, Santiago will once again try to turn a minors pact with the White Sox into a major league opportunity. He’ll have to perform better than he did as a Met, though. While Santiago did log a 3.35 ERA over 43 innings with the Mets’ Triple-A affiliate this year, his run prevention success came with far less encouraging peripherals. The 31-year-old then fell flat over eight innings with New York, where he gave up six earned runs on 10 hits and five walks (with six strikeouts).